Bone Morphogenetic Protein-2 Signaling in the Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells Induced by Pulsed Electromagnetic Fields

Disclaimer: this research study’s copyright belongs to the authors and PubMed and not HealthMatReview.com, further details below.

Our Summary

Due to previous studies in the effects of PEMF on osteogenic activity of bone morphogenetic protein-2 (BMP2) , this study now focuses on the effects of PEMF and BMP2 on osteogenic differentiation. Mesenchymal stem cells (MSC) were exposed to 75 Hz frequency and 1.5 mT intensity PEMF. Results confirm the synergistic activity of BMP2 and PEMF on osteogenic differentiation.

Pubmed Study Link

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139765/

PDF Study Link

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139765/pdf/ijms-21-02104.pdf

Study Categories

bone healing, brittle bone, cartilage growth

Authors

[‘Fernanda Martini’, ‘Agnese Pellati’, ‘Elisa Mazzoni’, ‘Simona Salati’, ‘Gaetano Caruso’, ‘Deyanira Contartese’, ‘Monica De Mattei’]

PMID

32204349

PMCID

PMC7139765

Published Date

more study details

Frequency (Hz)

75

Frequency Range

High

Intensity (G)

15

Intensity Range

High

Waveform

unknown

PEMF/EMF/RF/LT

PEMF

Study Subject Types

human

Keywords Listed

BMP, osteogenic differentiation, mesenchymal stem cells, pulsed electromagnetic fields

Added Descriptive Keywords

brittle bone, bone formation, cartilage, muscle, tissue, blood vessel, human

Disclaimer

All intellectual property and copyright of this research study sourced from PubMed, is the property of the authors and associates and is not the property of HealthMatReview.com. This research study has been included in our custom PEMF research database for the educational purposes of our readers. The on page summary, added descriptive keywords and other study details are copyright of HealthMatReview.com and were added to improve the search function of this custom research database.

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