Pulsed electromagnetic fields increase osteogenetic commitment of MSCs via the mTOR pathway in TNF-? mediated inflammatory conditions: an in-vitro study

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Our Summary

Previous studies show that PEMF had beneficial effects on fracture healing, but the process is unclear. This study now focus on the effects of PEMF on osteogenic differentiation of mesenchymal stem cells (MSC) and how this is triggered. Findings suggest that PEMF activated mTOR pathway by modulating of proteins which resulted in osteogenic differentiation.

Pubmed Study Link

PDF Study Link

Study Categories

bone healing, brittle bone, cartilage growth

Authors

[‘Letizia Ferroni’, ‘Chiara Gardin’, ‘Oleg Dolkart’, ‘Moshe Salai’, ‘Shlomo Barak’, ‘Adriano Piattelli’, ‘Hadar Amir-Barak’, ‘Barbara Zavan’]

PMID

29572540

PMCID

PMC5865106

Published Date

more study details

Frequency (Hz)

Frequency Range

Intensity (G)

Intensity Range

Waveform

unknown

PEMF/EMF/RF/LT

ELF-PEMF

Study Subject Types

human

Keywords Listed

Added Descriptive Keywords

brittle bone, bone formation, cartilage, human

Disclaimer

All intellectual property and copyright of this research study sourced from PubMed, is the property of the authors and associates and is not the property of HealthMatReview.com. This research study has been included in our custom PEMF research database for the educational purposes of our readers. The on page summary, added descriptive keywords and other study details are copyright of HealthMatReview.com and were added to improve the search function of this custom research database.

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