Synergistic effect of a LPEMF and SPIONs on BMMSC proliferation, directional migration, and osteoblastogenesis

Disclaimer: this research study’s copyright belongs to the authors and PubMed and not HealthMatReview.com, further details below.

Our Summary

Due to the beneficial effects of PEMF on osteoporosis treatment and improving bone fracture healing, this study now aims to investigate the effect of PEMF on osteoblastogenesis utilizing superparamagnetic iron oxide nanoparticle (SPION)-labeled BMMSCs. Rats with SPION were exposed to 50 Hz frequency and 1.1 mT intensity low-frequency pulsed electromagnetic field (LPEMF). Results confirm that the combined LPEMF and SPION stimulated migration and osteogenic differentiation of BMMSCs which can be used in bone defect treatment.

Pubmed Study Link

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992538/

PDF Study Link

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992538/pdf/ajtr0010-1431.pdf

Study Categories

bone healing, brittle bone

Authors

[‘Shaoyu Wu’, ‘Qiang Yu’, ‘Yang Sun’, ‘Jing Tian’]

PMID

29887957

PMCID

PMC5992538

Published Date

more study details

Frequency (Hz)

50

Frequency Range

Low

Intensity (G)

11

Intensity Range

High, Low

Waveform

unknown

PEMF/EMF/RF/LT

PEMF

Study Subject Types

animal

Keywords Listed

Pulsed electromagnetic fields, bone marrow mesenchymal stem cells, superparamagnetic iron oxide nanoparticles, osteoblastogenesis

Added Descriptive Keywords

bone, bone matrix, bone formation, bone marrow, tissue, bone defect, osteogenesis, osteoporosis, rat

Disclaimer

All intellectual property and copyright of this research study sourced from PubMed, is the property of the authors and associates and is not the property of HealthMatReview.com. This research study has been included in our custom PEMF research database for the educational purposes of our readers. The on page summary, added descriptive keywords and other study details are copyright of HealthMatReview.com and were added to improve the search function of this custom research database.

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