Increasing Odontoblast-like Differentiation from Dental Pulp Stem Cells through Increase of ?-Catenin/p-GSK-3? Expression by Low-Frequency Electromagnetic Field

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Our Summary

The objective of this study is to evaluate the ability of PEMF to induce differentiation and manage cell metabolism as well as identify the which frequency will have the highest efficacy. Stem cells of human dental pump were cultured and exposed to PEMF at 40, 60, 70 and 1500 Hz for 15 days at an intensity of 10 mT. Results showed that by increasing p-GSK-3? and ?-catenin expression, PEMF stimulated differentiation to odontoblast-like cells.

Pubmed Study Link

PDF Study Link

Study Categories

dental

Authors

[‘Han-Moi Lim’, ‘Myeong-Hyun Nam’, ‘Yu-Mi Kim’, ‘Young-Kwon Seo’]

PMID

34440255

PMCID

PMC8392719

Published Date

more study details

Frequency (Hz)

40, 60, 70, 150

Frequency Range

High, Low

Intensity (G)

100

Intensity Range

High

Waveform

unknown

PEMF/EMF/RF/LT

PEMF

Study Subject Types

human

Keywords Listed

human dental pulp stem cells, odontoblasts, pulsed electromagnetic field, odontogenesis, GSK-3?, ?-catenin

Added Descriptive Keywords

dental, teeth, dental pulp stem cells, odontoblasts, human

Disclaimer

All intellectual property and copyright of this research study sourced from PubMed, is the property of the authors and associates and is not the property of HealthMatReview.com. This research study has been included in our custom PEMF research database for the educational purposes of our readers. The on page summary, added descriptive keywords and other study details are copyright of HealthMatReview.com and were added to improve the search function of this custom research database.

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