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Our Summary
To investigate the effects of the combination of sinusoidal EMF (SEMF) and vascular endothelial growth factor (VEGF) on osteogenic and vasculogenic differentiation is the objective of this study. Results show that the combination of SEMF and VEGF improved protein expression level of osteo blast and mRNA expression level of endothelial cell. The treatment also stimulated angiogenic differentiation of rat bone marrow-derived mesenchymal stem cells indicating potential for bone regeneration therapy.
Pubmed Study Link
PDF Study Link
Study Categories
Authors
[‘Jingyuan Chen’, ‘Chang Tu’, ‘Xiangyu Tang’, ‘Hao Li’, ‘Jiyuan Yan’, ‘Yongzhuang Ma’, ‘Hua Wu’, ‘Chaoxu Liu’]
PMID
31842985
PMCID
PMC6915868
Published Date
more study details
Frequency (Hz)
Frequency Range
Intensity (G)
Intensity Range
Waveform
PEMF/EMF/RF/LT
Study Subject Types
Keywords Listed
Bone tissue engineering, Osteogenesis, Vascularization, Sinusoidal electromagnetic fields, Mesenchymal stem cell
Added Descriptive Keywords
bone, bone marrow, bone formation, muscle, tissue, bone regeneration, rat
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